Malaria News

Indonesian Health Minister Nafsiah Mboi
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22/07/2014 6:00:04 AM  from ABC Health     Read More      Permalink
Imported malaria in a non-endemic area: the experience of the university of Campinas hospital in the Brazilian Southeast
Although malaria in Brazil almost exclusively occurs within the boundaries of the Amazon Region, some concerns are raised regarding imported malaria to non-endemic areas of the country, notably increased incidence of complications due to delayed diagnoses. However, although imported malaria in Brazil represents a major health problem, only a few studies have addressed this subject. A retrospective case series is presented in which 263 medical charts were analysed to investigate the clinical and epidemiological characterization of malaria cases that were diagnosed and treated at Hospital & Clinics, State University of Campinas between 1998 and 2011. Amongst all medical charts analysed, 224 patients had a parasitological confirmed diagnosis of malaria.
22/07/2014  from Malaria Journal     Read More      Permalink
HIV, TB and malaria down globally: study
Campbell Cooney speak to study co-founder Professor Allen Lopez, from Melbourne University, about a new report from 188 countries on HIV, tuberculosis and malaria deaths and infections.
22/07/2014  from ABC Health     Read More      Permalink
Global study finds major decline of death, infections from HIV, tuberculosis and malaria - Australia Network News (Australian Broadcasting Corporation)
Researchers are hailing a significant drop in the number of deaths and infections worldwide from HIV, tuberculosis and malaria.
22/07/2014  from ABC Health     Read More      Permalink
New drug against malaria effective: Uses synchrotron light
The CD27 drug is a true alternative against malaria, researchers now report. They have analyzed the crystalline structure of the DNA with the drug by performing X-ray diffraction experiments at the ALBA synchrotron.
21/07/2014 10:01:53 AM  from Science Daily     Read More      Permalink
Indonesia's health minister works with Global Fund towards AIDS response - Australia Network News (Australian Broadcasting Corporation)
Indonesia's Health Minister Nafsiah Mboi says her nation's response to HIV and AIDS in partnership with the Global Fund to Fight AIDS, Tuberculosis and Malaria is heading in the right direction.
21/07/2014  from ABC Health     Read More      Permalink
Chitinase 3-like 1 is induced by Plasmodium falciparum malaria and predicts outcome of cerebral malaria and severe malarial anaemia in a case-control study of African children
Severe and fatal malaria are associated with dysregulated host inflammatory responses to infection. Chitinase 3-like 1 (CHI3L1) is a secreted glycoprotein implicated in regulating immune responses. Expression and function of CHI3L1 in malaria infection were investigated. Plasma levels of CHI3L1 were quantified in a case-control study of Ugandan children presenting with Plasmodium falciparum malaria. CHI3L1 levels were compared in children with uncomplicated malaria (UM; n = 53), severe malarial anaemia (SMA; n = 59) and cerebral malaria (CM; n = 44) using the Kruskall Wallis-test, and evaluated for utility in predicting fatal (n = 23) versus non-fatal (n = 80) outcomes in severe disease using the Mann Whitney U test, receiver operating characteristic curves, and combinatorial analysis.
21/07/2014  from Malaria Journal     Read More      Permalink
DDX39B (BAT1), TNF and IL6 gene polymorphisms and association with clinical outcomes of patients with Plasmodium vivax malaria
DDX39B (BAT1) encodes an RNA helicase known to regulate expression of TNF and IL-6. Elevated levels of these two cytokines are associated with increased severity of clinical malaria. The aim of this study was to investigate the relationship between single nucleotide polymorphisms (SNPs) in the DDX39B, TNF and IL6 genes and the clinical outcomes of patients with Plasmodium vivax malaria. Cross-sectional investigations were carried out in two regions of the Brazilian Amazon where several studies on the pathogenesis of vivax malaria had been performed. Individuals were categorized according to infection status as well as clinical presentation into the following groups: uninfected, asymptomatic infection, mild infection, or complicated infection.
19/07/2014  from Malaria Journal     Read More      Permalink
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